XINYU (ERIC) WANG, PHD
Department of Pharmaceutical Sciences
Assistant Professor


Xinyu 'Eric' Wang

Contact

Email: xinyuwa@pcom.edu
Office: 678-407-7365
Research Page

Dr. Wang received his Bachelor of Science degree in Pharmacy from the School of Pharmaceutical Sciences at Peking University in Beijing, China. He earned his Ph.D. in pharmaceutics from the University of Texas at Austin followed by postdoctoral training at the U.S. Army Institute of Surgical Research at San Antonio, Texas.

Dr. Wang joined PCOM School of Pharmacy in 2010 right before the start of its inaugural class. As a founding member, he is mainly involved in teaching pharmaceutics related courses including Biopharmaceutics, Pharmacokinetics, Pharmaceutical Compounding, and Pharmaceutical Calculation. He devoted himself to the development of an effective and rigorous curriculum and focused on improving student learning outcome. He also mentors PharmD and Biomed Thesis students in research projects and guides them to present their research outcome at local and national scientific meetings. His effort in teaching is highly appreciated by PharmD students who chose him as Teacher of the Year in 2014.

Dr. Eric Wang’s research interest is focused on the drug discovery and development to identify potential candidates with anti-cancer, anti-inflammatory, and anti-oxidant properties. He recently explored the inhibitory effects of compounds derived from natural sources on multiple myeloma, a plasma cell cancer characterized by the accumulation of malignant cells in bone marrow. His effort in multiple myeloma research was recognized, and he was recently named a 2016 American Association of Colleges of Pharmacy (AACP) New Investigator Award recipient. He has presented his research in various national and international conferences and published peer-reviewed articles in different pharmaceutical fields including medicinal chemistry, molecular pharmacology, pharmaceutical analysis, and pharmacokinetics.

Dr. Wang has served on many committees including curriculum, assessment, admissions, scholarship and awards, faculty development, faculty search, academic appeal, diversity and ACPE self-study. He participated in the ACPE accreditation process and contributed to the success of School of Pharmacy accreditation in 2014 and site visit in 2016.

  • Education

    PhD in Pharmaceutical Sciences, University of Texas at Austin, Austin, Texas, 2008
    BS in Pharmacy, Peking University Health Science Center, Beijing, China, 1997

  • Courses

    Biopharmaceutics
    Pharmacokinetics
    Pharmaceutics
    Pharmaceutics Compounding Lab
    Pharmaceutical Calculations

  • Research

    Dr. Eric Wang’s research interest is focused on the drug discovery and development to identify potential drug candidates with anti-cancer, anti-inflammatory, and anti-oxidant properties. Currently, he is investigating the effects of potential drug candidates from natural sources for the treatment of multiple myeloma, a cancer of plasma cells in the bone marrow. This disease remains incurable and results in 10 to 15 % of blood cancer and 20% human death related to blood and bone marrow cancer. His research is funded through PCOM intramural grants and supported by American Association of Colleges of Pharmacy (AACP) as he is the recipient of AACP New Investigator Award 2016. He has presented his research in various national and international conferences and published peer-reviewed articles in different pharmaceutical fields including medicinal chemistry, molecular pharmacology, pharmaceutical analysis and pharmacokinetics.

  • Awards

    AACP New Investigator Award, 2016
    Teacher of the Year 2014, PCOM School of Pharmacy, 2014
    Peach Teaching Award, PCOM School of Pharmacy, 2013
    Peach Teaching Award, PCOM School of Pharmacy, 2012
    Sigma Xi, the Scientific Research Society
    Phi Kappa Phi honor society
    Rho Chi honor society in pharmacy

  • Publications

    Wang X, Rayalam S, Bhave V. Heat Shock Proteins and Phytochemicals: Role in Human Health and Disease. In Asea, Alexzander A. A., Calderwood, Stuart, and Kaur, Punit (Eds.), Heat Shock Proteins and Plants, Springer International Publishing, Switzerland, Chapter 11:211-232, 2016.

    Mula RV, Machiah D, Holland L, Wang X, Parihar H, Sharma AC, Selvaraj P, Shashidharamurthy R. Immune Complex-induced, Nitric Oxide-mediated Vascular Endothelial Cell Death by Phagocytes is Prevented with Decoy FcgReceptors. PLOS ONE 2016: 11(4):e0153620.

    Wang X, Bynum J, Stavchansky S, and Bowman PD. Cytoprotection of human endothelial cells against oxidative stress by 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im): Application of systems biology to understand the mechanism of action. Eur J Pharmacol. 2014;734:122-31.

    Bowman PD, Wang X, Meledeo MA, Dubick MA, Kheirabadi BS. Toxicity of Aluminum Silicates Used in Hemostatic Dressings Toward Human Umbilical Veins Endothelial Cells, HeLa Cells, and RAW267.4 Mouse Macrophages. Journal of Trauma 2011; 71(3): 727-732.

    Yang J, Marriner GA, Wang X, Bowman PD, Kerwin SM, Stavchansky S. Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE). Bioorganic & Medicinal Chemistry 2010; 18(14): 5032-5038.

    Wang X, Stavchansky S, Kerwin SM, Bowman PD. Structure-activity relationships in the cytoprotective effect of caffeic acid phenethyl ester (CAPE) and fluorinated derivatives: Effects on heme oxygenase-1 induction and antioxidant activities. European Journal of Pharmacology 2010; 635(1-3): 16-22.

    Wang X, Pang J, Maffucci JA, Pade D, Newman RA, Kerwin SM, Bowman PD, Stavchansky S. Pharmacokinetics of caffeic acid phenethyl ester and its fluorinated derivative in rats. Biopharmaceutics & Drug Disposition 2009; 30(5): 221-228.

    Wang X, Stavchansky S, Zhao B, Bynum JA, Kerwin SM, Bowman PD. Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: The role of heme oxygenase-1. European Journal of Pharmacology 2008; 591(1-3): 28-35.

    Wang X, Pang J, Newman RA, Kerwin SM, Bowman PD, Stavchansky S. Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Chromatography B 2008; 867(1): 138-143.

    Wang X, Bowman PD, Kerwin SM, Stavchansky S. Stability of caffeic acid phenethyl ester and its fluorinated derivative in rat plasma. Biomedical Chromatography 2007; 21(4): 343-350.

    Wang X, Stavchansky S, Bowman PD, Kerwin SM. Cytoprotective effect of caffeic acid phenethyl ester (CAPE) and catechol ring-fluorinated CAPE derivatives against menadione-induced oxidative stress in human endothelial cells. Bioorganic &Medicinal Chemistry 2006; 14(14): 4879-4887.

  • Memberships

    American Association of Pharmaceutical Scientists
    American Association of Advancement of Science
    American Association of Colleges of Pharmacy
    American Society for Pharmacology and Experimental Therapeutics
    International Society for the Study of Xenobiotics

  • Other

    • BRB-ArrayTools Data Analysis workshop; NIH, Washington DC, July 14th, 2006.
    • Pharmacokinetic/Pharmacodynamic Modeling workshop; School of Pharmacy & Pharmaceutical Sciences, University at Buffalo, Buffalo, New York; May 18 ~ 21th, 2008.
    • Introductory Compounding Lab Training, PCCA, Houston, Texas; June 8 ~ 9th, 2015.